Tim Craggs

University of Sheffield

Tim Craggs is a lecturer at the University of Sheffield, UK (appointed 2016). He is an expert in the development and application of Förster Resonance Energy Transfer (FRET) methods to biological systems, with particular experience in DNA-protein interactions.  He completed his PhD (Cambridge, UK) developing single-molecule and ensemble methods to study protein folding. Subsequently, he helped to establish a new single-molecule lab (St Andrews) developing FRET approaches to study the structure-specific nucleases XPF and FEN1. He won a prestigious Lindemann Trust Fellowship to continue his investigation of DNA-protein interactions (specifically DNA Polymerase I) at Yale with Cathy Joyce (2010), and returned to the UK to work with Achillefs Kapanidis (Oxford, 2011) where he used smFRET to determine the structure and dynamics of a protein-DNA complex. His multidisciplinary skills span DNA and protein biochemistry, ensemble and single-molecule biophysics and molecular modelling. His current research is focussed on understanding the conformational dynamics of biomolecules.