Free

ESRIC Super-Resolution Summer School 2019

14 – 19 July 2019 + Add to calendar Edinburgh

Free

ESRIC Super-Resolution Summer School 2019

14 – 19 July 2019 + Add to calendar Edinburgh

The ESRIC super-resolution summer school is a five-day residential course held in Edinburgh. The course is designed to give participants a thorough grounding in super-resolution microscopy in an informal and intimate setting. It brings together leading academics and the major suppliers of super-resolution microscopes to provide expertise and guidance in the theory, practise and analysis of structured illumination microscopy (SIM), stimulated emission depletion microscopy (STED), AiryScan and single molecule localization microscopies (PALM, sptPALM and dSTORM).

The summer school will consist of informal lectures and workshops and participants will have ample time to gain project specific advice from all of the academic experts and suppliers through dedicated Q&A sessions and informal social events. The course is suitable for anyone with prior experience of fluorescence microscopy looking to exploit the benefits of super-resolution microscopy in their research.

Please scroll down the page to find further information about the course and to submit your application.

For news and details from the 2019 ESRIC Course please visit the ESRIC News pages.

Applications and registration

Applications and registration

Applications have now closed.

Speakers

Scientific Organiser

Dr Alison Dun

Heriot-Watt University
Alison is the facility manager for the Edinburgh Super-Resolution Imaging Consortium (ESRIC) and is based at the Heriot-Watt University site. Alison completed her PhD at the University of Edinburgh in 2013 where she used a wide range of advanced imaging techniques to study cell membrane biology. Alison now works in an interdisciplinary environment, running the imaging facility at the Institute of Biological Chemistry, Bioengineering and Biophysics at Heriot-Watt University.
Dr Ann Wheeler

University of Edinburgh
Ann is a cell biologist and our University of Edinburgh ESRIC facility manager with expertise in advanced light microscopy in particular in Structured Illumination Microscopy (SIM) and Single Molecule Localisation Super-resolution microscopy (SMLM) as well as quantitative image analysis. Ann works with collaborators in the generation of new methods and methodologies for visualising structures by super-resolution.
Laura Murphy

IGMM, Edinburgh

Invited Speakers

Dr Susan Cox

King's College London
Susan works at the Randall Centre for Cell and Molecular Biophysics, developing fluorescence microscopy techniques and applying them to discover new cell biology at the nanoscale. In 2011 she was awarded a Royal Society University Research Fellowship, which she used to develop a substantial research program based around localisation microscopy, and methods to extract more information from super-resolution image data. SC is best known as the developer of Bayesian analysis of blinking and bleaching (3B), a method for analysing extremely dense localisation microscopy image series. Its importance has been recognised with the award of the Royal Microscopical Society light microscopy medal and the Society of Experimental Biology Presidents Medal. More recently, she has explored the limits of localisation in terms of speed and accuracy. She mathematically described the role of the size of the point spread function size in limiting information transmission speed and developed a machine learning based approach to remove poor fits from the super resolution image. Since it is obviously more desirable to avoid poor fits in the first place, she developed Haar Wavelet Kernel analysis (HAWK), an approach to localisation microscopy data analysis which avoids artifacts and ensures the results reflect the underlying structure of the sample.
Rory Duncan

Heriot-Watt

Rory Duncan (University Senior Academic Lead for Strategy and Development) was founding Head of the Institute of Biological chemistry, Biophysics and Bioengineering at Heriot-Watt University, applying advances in EPS to life science challenges. He is PI and Co-Director of the Edinburgh super-resolution imaging consortium (ESRIC, www.esric.org) with support from MRC/BBSRC/EPSRC and the Wellcome Trust, developing and applying super-resolution imaging modalities. This programme of work was awarded the Times Higher ‘STEM Research Project of the Year’.

Rory’s work spans many Disciplines and he has publications in leading biology, chemistry, engineering and physics journals, and he holds multiple patents. Rory sits on as is ad hoc Chair of STFC Science Board, the principal scientific advisory committee providing strategic oversight on all research activities for that Research Council and is part of the Accelerator International Strategic Review Panel, shaping Big Science strategy for the next 25 years. He is a member of the Scottish Parliamentary Cross-Party Group for Life Sciences.

Rory has won several awards for science communication and was awarded the Royal Society of Edinburgh Senior Medal for Public Engagement in 2018 for his ‘passion and enormously productive advocacy for public engagement in Scotland, the UK and internationally’. His current role is as Senior Academic Lead for Strategy and Development for Heriot-Watt University as well as of Academic Lead for Public Engagement with Research. In the latter role, Rory holds external funds to develop public engagement strategy for the university with an emphasis on community engagement and embedding public engagement in university culture.
Jonathan Grimm

Janelia Research Campus
Jonathan Grimm is a synthetic organic chemist and senior scientist in the laboratory of Luke Lavis at the Janelia Research Campus of the Howard Hughes Medical Institute in Ashburn, Virginia, USA. Jon received a B.S. in Chemistry from the University of Virginia in 2002. He then attended graduate school at the University of Wisconsin-Madison, completing an M.S. in Chemistry while investigating silicon-tethered enyne metathesis with Daesung Lee. From 2005 to 2010, Jon worked as a medicinal chemist at Merck Research Laboratories in Boston, Massachusetts. Since 2010, he has worked in the Lavis laboratory at Janelia. In his work with Lavis, Jon has focused on the application of organic synthesis to the preparation of innovative tools for biology and microscopy, including fluorescent dyes and fluorogenic molecules. He seeks to leverage new technologies in the synthetic community and opportunistically develop novel chemistry to modernize dye synthesis and access new chemical space.
Professor Ricardo Henriques

Instituto Gulbenkian de Ciência, Portugal
Ricardo Henriques is a Particle Physicist by training that fell in love with Biological Physics shortly after graduating. He carried out his PhD studies in both the Musa Mhlanga and Christophe Zimmer laboratories, doing research between IMM (Portugal), Institut Pasteur (France), CSIR (South Africa) and Andor Technology (UK and USA). During this time, he entered the field of Super-Resolution Microscopy, developing technologies that enable imaging of cellular and viral structures at unprecedented resolution. During his PhD and postdoc, he applied the methods he developed to study Cell Signalling, T-cell Immunology and Viral Infection. In 2013 he established his first research group at UCL, with a dual emphasis on Developing new Imaging Technologies and Cell Biology research. In 2017 he was further invited to extend my group into the Francis Crick Institute, where he established a second small laboratory. In 2019 he was promoted to full Professor at UCL and in 2020 established a new laboratory at Instituto Gulbenkian de Ciência in Portugal. His technological developments are widely disseminated to the Cell Biology and Biomedical research community. Ricardo and his team developed algorithms, such as QuickPALM, NanoJ, SRRF and SQUIRREL, which are among the most used analytical methods in the Super-Resolution Microscopy field. His core philosophy has been to make research reproducible, transparent, and open-source.
Jonas Ries

EMBL - Heidelberg

PhD 2008, TU Dresden with Prof. Petra Schwille on Fluorescence Correlation Spectroscopy to study membrane dynamics.
2009-2012 Postdoctoral research at the ETH Zurich with Prof. Helge Ewers on superresolution microscopy.
Since 2012 Group Leader at the EMBL Heidelberg. The Ries group studies nanoscale multi-protein machineries in their functional cellular context, and elucidates their dynamic structural organisation using tailor-made superresolution microscopy technologies.
Professor Dr Silvio Rizzoli

The Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB)

Silvio O. Rizzoli, PhD, completed a BSc in biochemistry in 2000 at the University of Bucharest, Romania. He then carried out graduate training, until 2004, in the laboratory of Dr. William Betz at the University of Colorado. Dr. Rizzoli studied synaptic function for his PhD, and then trained as a postdoctoral fellow in the laboratory of Dr. Reinhard Jahn at the Max-Planck-Institut for Biophysical Chemistry in Göttingen, Germany, again focusing on synaptic function. Since 2007, he has led his own laboratory, first as a group leader and then as a professor at the University of Göttingen Medical Center.

Silvio’s laboratory has a dual focus – high-end imaging and cutting edge research in synaptic physiology. All projects that are run make use of advanced imaging techniques, including STED and electron microscopy.
Dr Markus Sauer

University of Würzburg

Markus Sauer studied Chemistry at the University Heidelberg where he received his Diploma in 1991. He finished his PhD 1995 in Physical Chemistry under the supervision of Prof. Dr. Jürgen Wolfrum. 1998 he has been awarded the BioFuture Prize for Detection, Analysis and Handling of Single Molecules, which allowed him to establish his own group for single-molecule fluorescence detection and single-molecule DNA sequencing. Since 2009 he is Professor and Chair of the Department of Biotechnology and Biophysics at the Julius Maximilian University Würzburg. His research interests are single-molecule fluorescence spectroscopy and imaging with a particular focus on super-resolution fluorescence imaging by direct stochastic optical reconstruction microscopy (dSTORM) and its applications in neurobiology and immunology. He has published more than 250 journal papers and coordinates several national super-resolution microscopy projects.
Ilaria Testa

KTH Royal Institute of Technology in Stockholm

I performed my PhD between 2006-2009 at the University of Genoa (Italy) in the group of Prof. A. Diaspro working on the use of Photo-switchable Fluorescent Proteins for cellular trafficking.
Between 2009-2014 I worked as a Postdoc Researcher in the group of the Nobel Laureate Prof. S.W. Hell at the MPI-BS in Göttingen (Germany). During this time I actively developed several nanoscopes based on (1) single molecule switching for multicolour imaging (2) RESOLFT nanoscopy. Within an interdisciplinary team of biologists and physicists we succeeded to apply the RESOLFT concept in living cells and even tissues for the first time.
Since 2015 I’m Professor at KTH SciLife fellow at the SciLifeLab in Stockholm (Sweden). The goal of my group is to develop next generation fluorescence nanoscopy approaches to address contemporary challenges in biophysics and molecular biology. A special effort will be dedicated to investigate the nanoscale organization of neuronal processes at high spatio/temporal resolution.
Dr Andrew York

Calico

Andrew York is a physicist with a background in optics, an interest in invention, and no training in biology. His postdoctoral work produced the technology behind superresolution microscopes like the Yokogawa CSU-W1 SoRa, the VisiTech VT-iSIM, and the Oxford Nanoimager's SIM mode. His group at Calico Labs currently works on microscopy projects related to lightsheet, stimulated emission, deconvolution, photophysics, and fluorophore development. See andrewgyork.github.io for their recent publications.

Delegate information

Registration fees
Registration and accommodation package

Standard rate including 5 nights' accommodation - £900
RMS Member rate including 5 nights' accommodation - £850
Student rate including 5 night’s accommodation – £800
Optional 6th night of accommodation on Friday 19 July - £50

Registration package

Standard rate - £650
RMS Member rate - £600
Student rate – £550

Bursaries
Bursary applications have now closed.

Venue for the Course
The ESRIC Summer School is based at the Heriot-Watt University, Edinburgh Campus, Edinburgh, EH14 4AS.
For more information about the University, please visit the Heriot-Watt website.

Delegates will also visit ESRIC’s second facility at the Institute of Genetics and Molecular Medicine at the University of Edinburgh during the week.

Travelling to the venue
Car – There is limited parking at the campus, but we advise using public transport where possible.

Train – Edinburgh Waverley is the main train station for Edinburgh. Regular buses depart from near the station to the campus. We do not recommend alighting at either Edinburgh Park or Curriehill as there is no direct transport link to the campus from these stations.

Air - Edinburgh International Airport is served by scheduled national and international flights. The campus is a short journey by taxi from the airport.

Accommodation
The accommodation is likley to be on campus in an en-suite student room.

Delegates can check in from the Sunday afternoon.

Lunch and refreshments are included in your registration fee.

Dietary and Access requirements
The RMS is committed to our delegate’s health and wellbeing. Therefore if you have any dietary or access requirements please contact Karina Lang.

Registration
Admittance to this event is for registered and authorised attendees. Unfortunately we cannot permit access to visitors or allow non-registered persons to enter the meeting or exhibition areas. If you have any questions, please contact the RMS contact for this event.

ESRIC Super-Resolution Summer School 2019