1st Prize Electron Microscopy Life Sciences. A three-dimensional computer model showing part of the intercalated disc, the undulating double membrane that separates adjacent cardiomyocytes. The model was constructed from an electron tomogram. The membrane is shown in olive green, mitochondria; purple, sarcoplasmic reticulum; pale blue, gap junctions; dark green, desmosomes; red. Field size; 4.7x2.7x0.4um. Author, Amanda Wilson
2nd Prize Electron Microscopy Life Sciences. This is a high magnification and coloured image of a fruitfly compound eye. In normal tissue, the structure of the eye is very repetitive and highly organised, but here is an example of a mutant eye where the tissue structure is barely recognisable. The cells of this eye are overexpressing a protein called Yorkie, which leads to the formation of tumours. We can see strange protrusions (yellow) and tunnel-like structures with holes (in brown) that are never found in a normal eye. The brown structure engendered by this mutation has been dubbed a ³wart², and this particular ³wart² forms a cute little alien face that seems, for good reasons, a bit bewildered to find itself here! (Sample material provided by A. Genevet, sample preparation and picture by K. Blight, colourisation by A. Weston). Author, Ken Blight
3rd Prize Electron Microscopy Life Sciences. Three-dimensional reconstruction of an apical dendrite of a pyramidal cell from the cerebral cortex; apart the dendrite, the axial view includes also surrounding astrocyte processes with glycogen particles. Serial electron microscopy, Jeol transmission electron microscope, prim. magn. 30 000 x. Author, Josef Spacek
1st Prize Electron Microscopy Physical Sciences. Scanning Probe Microscopes (SPMs) provide a whole new physical toolkit for nanoscale forces and interactions. This SEM image shows a polymer bead attached to a silicon-nitride cantilever so its stiffness can be estimated by SPM, using tiny forces to squash the bead against a hard surface. 5kV, Field-width 115µm. Author, Paul Gunning
2nd Prize Electron Microscopy Physical Sciences. SEM - high vacuum. NaCl crystal and C reactive protein. Author, Ken Png
3rd Prize Electron Microscopy Physical Sciences. An SEM micrograph showing structural modifications of a thermocompression gold ball bond. Author, Jonathan Ogden
1st Prize Light Microscopy Life Sciences. Pseudo darkfield image showing the proboscis of a Blowfly from a slide by Norman. Sony Cybershot W50 digital camera attached to an Olympus widefield eyepiece coupled with a x3.7 Lomo achromatic objective lens on a Russian Biolam microscope. Author, Michael Gibson
2nd Prize Light Microscopy Life Sciences. Darkfield photomicrograph. Author Harold Taylor
3rd Prize Light Microscopy Life Sciences. Cultured mouse fibroblast immunostained for alpha tubulin(green) and Vimentin(red). Imaged in a confocal microscope. Author, David Robertson
1st Prize Light Microscopy Physical Sciences. BF polarised illumination. Author, Karl Deckart
2nd Prize Light Microscopy Physical Sciences. Ascorbic Acid crystals photographed by cross-polarization. Author, Michael Much
3rd Prize Light Microscopy Physical Sciences. lilluminated by tree external swanneck lamps via monochrome filters. Author, Karl Deckart
1st Prize Scanning Probe Microscopy.
Constant current Scanning Tunnelling Microscopy image of a porphyrin nanoring network on a HOPG surface imaged in liquid. Each nanoring consists of 12 covelently-linked porphyrin monomers. Image size 25 x 25 nm. Author, Alex Summerfield