Since its inception, fluorescence imaging has revolutionised biological research, providing an invaluable tool for scientists to explore and visualise cellular structures and processes at a microscopic scale.
Scanning electron microscopes (SEMs) are popular imaging tools across a wide range of research and industrial applications, enabling clear view at nanometre scales due to their unparalleled magnification
capabilities.
After some 350 years, newly discovered Leeuwenhoek microscopes are emerging. Two have now been subject to examination with the scanning electron microscope (SEM).
Fluorescence microscopy is an essential tool in cell biology as it allows scientists to look at what is inside of a cell and easily see the organisation of organelle by labelling different organelles selectively.
Supported by an RMS Summer Studentship award, I spent time in the lab of Professor Duncan Graham at the University of Strathclyde to study the uptake and distribution of Bruton’s tyrosine kinase (Btk) inhibitors, ibrutinib, acalabrutinib and ibrutinib-yne using a combination of Raman and stimulated Raman scattering microscopy.
Through the loan of a portable Scanning Electron Microscope (SEM), this successful outreach programme focuses on bringing research directly to schools.
With the dust now settled on mmc2023 (incorporating EMAG 2023), we take a look back at what proved to be a fantastic few days in Manchester, celebrating the very best in microscopy, imaging and flow cytometry.
Brightfield microscopy has been a viable observation technique for cytology and histological analysis employing stained cells and tissue sections mounted on a microscope slide.
