Frozen Tissue
Frozen tissues samples have been widely used in medical research for cancer and other diseases to examine cell morphology, disease status, intracellular and intercellular communication, as well as biopsy tissue sections.
Compared to FFPE sample preparation, freezing has the advantage of being fast, and the resulting samples are very suitable for molecular analysis. Frozen tissue samples are also preferred in analysis such as mass spectrometry, next generation sequencing, western blotting for post-translational protein modifications, and quantitative real-time polymerase chain reaction. Therefore, frozen tissue samples are the gold standard for DNA and RNA sequencing, especially when the strands must be longer than 50 pairs. In immunohistochemistry, frozen tissue samples are also very useful as the proteins are preserved in a native state.
Created: 27 Dec 2024 07:12:49 AM
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